| The oyster Crassostrea gigas is one of the most commercialized molluscs in the world. It is a very cosmopolitan species that has been disseminated by humans and is susceptible to various agents such as pathogens (bacteria, viruses), parasites, xenobiotics and/or toxic micro-algae. As a filter-feeder, it may accumulate phyco- toxins while feeding on harmful algal blooms (HAB), including paralytic shellfish toxins (PST). To protect human health shellfisheries harvesting are closed dur- ing HAB, impacting the aquaculture industry. This PhD work aims to develop a Dynamic Energy Budget (DEB) based model to describe kinetics of PST accumulation and detoxification in C. gigas. Interest of coupling bio-accumulation to DEB model lies in the inclusion of... |
